Description

Homoharringtonine is a potent alkaloid derived from the *Cephalotaxus* genus of evergreen trees. This compound is of significant interest for its specific biological activity and serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in oncology and life science studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents.
• Oncology Studies: Used as a biochemical tool in cancer research to study mechanisms of protein synthesis inhibition and apoptosis.
• Life Science Laboratories: Employed in cell biology and pharmacology research to investigate its effects on various cell lines.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex derivatives and analogs for structure-activity relationship (SAR) studies.
• Quality Control & Analytical Testing: Used as a certified reference material (CRM) in HPLC, LC-MS, and other analytical methods to ensure accuracy and compliance.

Basic Information

Product Name	Homoharringtonine
CAS No.	26833-87-4
Molecular Formula	C29H39NO9
Molecular Weight	545.62 g/mol
Synonyms	Omacetaxine Mepesuccinate; HHT; Ceflatonin; NSC 141633; Harringtonine analog; (2'R)-2'-Deoxy-2'-(hydroxymethyl)harringtonine; 2-(2-Hydroxy-2-methylbutyryl)cephalotaxine ester
EINECS	Contact for details

Quality Control

Our Homoharringtonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.