Description

Harringtonine is a naturally occurring alkaloid ester derived from the *Cephalotaxus* genus, recognized for its potent biological activity. This compound is a critical reference standard and active pharmaceutical ingredient (API) for advanced research and development in oncology. It is essential for pharmaceutical manufacturers, academic research institutions, and biotechnology companies focused on cancer therapeutics and cell biology studies.

Application

• Oncology Research: As a key reference standard in studies investigating protein synthesis inhibition and apoptosis induction in cancer cells.
• Pharmaceutical Development: Serves as an active pharmaceutical ingredient (API) or intermediate in the formulation of investigational anti-cancer drugs.
• Biochemical Research: Used as a selective inhibitor in molecular biology to study mechanisms of cell cycle arrest and ribosomal function.
• Quality Control & Analytical Testing: Employed as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical methods in pharmaceutical QC labs.
• Academic Studies: Utilized in university and institutional research for pharmacological and toxicological profiling.

Basic Information

Product Name	Harringtonine
CAS No.	26833-85-2
Molecular Formula	C28H37NO9
Molecular Weight	531.60 g/mol
Synonyms	Harringtonine; Cephalotaxine, 4-methyl-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (ester); (+)-Harringtonine; NSC 56367; Homoharringtonine (closely related analogue); Cephalotaxus alkaloid
EINECS	Contact for details

Quality Control

Our Harringtonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade and pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.