Description

Prostaglandin A1 Methyl Ester is a chemically modified derivative of the naturally occurring prostaglandin A1, designed to enhance stability and handling for research and development purposes. This compound serves as a crucial biochemical tool and synthetic intermediate in the study of prostaglandin pathways and their physiological effects. It is primarily utilized by pharmaceutical researchers, academic institutions, and fine chemical manufacturers engaged in the development of novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Research & Development: Acts as a key reference standard and synthetic precursor in the investigation of prostaglandin receptor activity and the development of anti-inflammatory, cardiovascular, and oncological drug candidates.
• Biochemical Studies: Used as a tool compound to study cellular signaling pathways, enzyme inhibition (e.g., cycloxygenase), and the biological roles of PGA derivatives in various disease models.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for the organic synthesis of more complex prostaglandin analogs and specialized bioactive molecules.
• Academic Research: Employed in university and institutional laboratories for fundamental research in physiology, pharmacology, and medicinal chemistry.
• Standards & Calibration: Used to prepare high-purity analytical standards for quality control and method development in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	Prostaglandin A1 Methyl Ester
CAS No.	26771-94-8
Molecular Formula	C₂₁H₃₂O₅
Molecular Weight	364.48 g/mol
Synonyms	PGA1 Methyl Ester; Methyl (5Z,13E)-(9S,11R,15R)-9,11,15-Trihydroxyprosta-5,13-dien-1-oate; 15(R)-PGA1 Methyl Ester; Methyl 15(R)-PGA1; Prostaglandin A1 ME; PGA1-ME; (15R)-Prostaglandin A1 Methyl Ester
EINECS	Contact for details

Quality Control

Our Prostaglandin A1 Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.