Description

15-Keto Prostaglandin E2 is a biologically significant prostaglandin metabolite and a key intermediate in eicosanoid research. This compound is crucial for studying the metabolic pathways and biological activities of prostaglandins, particularly in relation to inflammation, cell signaling, and physiological regulation. It is an essential biochemical tool for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, where precise and high-purity reference standards are required.

Application

• Biochemical Research: Used as a critical reference standard and analytical standard in prostaglandin and eicosanoid metabolism studies.
• Pharmaceutical Development: Serves as a key intermediate or metabolite for the development and validation of new anti-inflammatory drugs and therapeutics.
• Cell Signaling Studies: Employed in in vitro and in vivo research to investigate the role of prostaglandin metabolites in cellular communication and physiological processes.
• Metabolite Analysis: Essential for analytical method development in LC-MS, GC-MS, and HPLC for the quantification of prostaglandin pathways in biological samples.
• Enzyme Activity Assays: Used as a substrate or product in assays to study the activity of enzymes like 15-hydroxyprostaglandin dehydrogenase (15-PGDH).
• Academic Research: A vital reagent for universities and research institutes focusing on lipidomics, inflammation biology, and metabolic disorders.

Basic Information

Product Name	15-Keto Prostaglandin E2
CAS No.	26441-05-4
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	15-Keto-PGE2; 15-Oxoprostaglandin E2; 11α,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2 15-ketone; 15-Ketoprostone; Prostaglandin E2 15-ketone; 15-Keto-PGE₂; 15-Oxo-PGE2
EINECS	Contact for details

Quality Control

Our 15-Keto Prostaglandin E2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.