Description

Pepstatin CAS NO 26305-03-3 is a potent, naturally occurring protease inhibitor that specifically targets aspartic proteases like pepsin, renin, and cathepsin D. This specificity makes it an indispensable biochemical tool for research and development in life sciences. It is primarily utilized by pharmaceutical researchers, biochemists, and diagnostic manufacturers for enzyme inhibition studies, protein purification, and the development of therapeutic agents.

Application

• Inhibition of aspartic proteases (e.g., pepsin, renin, cathepsin D) in biochemical and pharmacological research.
• Critical reagent in protease activity assays and enzyme characterization studies.
• Used in protein purification protocols to prevent unwanted proteolytic degradation.
• Tool compound for studying diseases related to aspartic protease dysfunction, such as hypertension and certain cancers.
• Component in diagnostic kit development for measuring specific protease activities.
• Research into HIV-1 protease inhibition due to structural similarities.

Basic Information

Product Name	Pepstatin
CAS No.	26305-03-3
Molecular Formula	C34H63N5O9
Molecular Weight	685.89 g/mol
Synonyms	Pepstatin A; Isovaleryl-Val-Val-Sta-Ala-Sta; (3S,4S)-4-[(2S)-2-[(2S,3S)-3-Amino-2-hydroxy-4-phenylbutanoyl]amino-3-methylbutanoyl]oxy-3-[(1S)-1-carboxy-2-methylbutyl]amino-4-oxobutanoic acid; Iva-Val-Val-Sta-Ala-Sta; Aspartic Protease Inhibitor
EINECS	247-139-5

Quality Control

Our Pepstatin is produced and tested under stringent quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency. We adhere to relevant industry standards for biochemical reagents, ensuring reliable performance in sensitive assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in methanol, DMSO, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.