Description

4Alpha-Phorbol is a diterpene ester of significant interest in biochemical and pharmacological research. This compound matters as a key reference standard and tool compound for studying protein kinase C (PKC) activation and tumor promotion mechanisms. Researchers in the pharmaceutical, biotechnology, and academic sectors need it for investigating signal transduction pathways, developing cancer therapeutics, and conducting toxicological studies.

Application

• As a reference standard for analytical method development and quality control in pharmaceutical research.
• For biochemical research on protein kinase C (PKC) activation and related signal transduction pathways.
• In cancer research as a tumor-promoting agent for studying carcinogenesis and testing potential chemopreventive agents.
• Utilized in toxicology studies to understand the mechanisms of phorbol ester toxicity.
• As a biological tool compound in cell-based assays to induce specific cellular responses.
• For academic research and teaching within university chemistry and biology departments.

Basic Information

Product Name	4Alpha-Phorbol
CAS No.	26241-63-4
Molecular Formula	C20H28O6
Molecular Weight	364.44 g/mol
Synonyms	4α-Phorbol; Phorbol, 4α-; 4alpha-Phorbol; 4-α-Phorbol; 4α-Phorbol (9CI); NSC 56439; 1,1a,1b,4,4a,7a,7b,8,9,9a-Decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one
EINECS	Contact for details

Quality Control

Our 4Alpha-Phorbol is produced and tested to meet the stringent requirements of research and development. Each batch undergoes rigorous analytical characterization to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.