Description

1A,1B-Dihomoprostaglandin E2 is a synthetic prostaglandin analog, a key intermediate in the synthesis of advanced pharmaceutical compounds. This high-purity intermediate is critical for researchers and manufacturers requiring precise control over molecular structure for biological activity studies. It is primarily utilized in the pharmaceutical and life science research sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of prostaglandin-based drugs and advanced active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and precursor in studies investigating prostaglandin receptor activity, signaling pathways, and metabolic processes.
• Medicinal Chemistry: Serves as a core scaffold for the design and development of new chemical entities with potential therapeutic applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of specialized pharmaceutical compounds.

Basic Information

Product Name	1A,1B-Dihomoprostaglandin E2
CAS No.	26198-80-1
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	1a,1b-Dihomo-PGE2; DH-PGE2; 7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic Acid; (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic Acid; 1a,1b-Dihomoprostaglandin E2; Prostaglandin E2 Dihomo Analog
EINECS	Contact for details

Quality Control

Our 1A,1B-Dihomoprostaglandin E2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.