Description

2,4-Dichlorobenzenesulfonyl Fluoride is a versatile organosulfur compound and a key fluorinated sulfonylating reagent. Its primary value lies in its high reactivity as a sulfonyl fluoride, enabling efficient synthesis of sulfonamides, sulfonate esters, and other functionalized intermediates under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical building block for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of sulfonamide-based drugs, including protease inhibitors, diuretics, and antibacterial agents.
• Agrochemical Synthesis: Used to create novel sulfonylurea herbicides and fungicides, contributing to crop protection solutions.
• Chemical Probe Development: Employed in chemical biology and proteomics as a reactive handle for activity-based protein profiling (ABPP) due to its specific reactivity with serine hydrolases.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers with sulfonyl fluoride functionalities.
• Organic Synthesis Reagent: Acts as a robust electrophile in nucleophilic substitution reactions to introduce the 2,4-dichlorobenzenesulfonyl moiety into target molecules.
• Dye & Pigment Manufacturing: Utilized in the production of sulfonated dyes and colorants, enhancing solubility and performance properties.

Basic Information

Product Name	2,4-Dichlorobenzenesulfonyl Fluoride
CAS No.	26120-88-7
Molecular Formula	C6H3Cl2FO2S
Molecular Weight	229.05 g/mol
Synonyms	2,4-Dichlorobenzene-1-sulfonyl fluoride; 1,3-Dichloro-4-fluorosulfonylbenzene; 2,4-Dichlorophenylsulfonyl fluoride; Benzenesulfonyl fluoride, 2,4-dichloro-; 2,4-DCBSF; 2,4-Dichlorobenzenesulfonoyl fluoride
EINECS	Contact for details

Quality Control

Our 2,4-Dichlorobenzenesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent hydrolysis. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.