Description

3-(Difluoromethyl)-1-Fluorobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique difluoromethyl and fluorine substituents make it a critical intermediate for introducing fluorine atoms into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties such as metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the synthesis of semiconducting materials and charge-transport layers for OLEDs and other electronic devices.
• Fluorinated Polymer Modifiers: Acts as a monomer or modifier to impart specific properties like chemical resistance and low surface energy to specialty polymers.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	3-(Difluoromethyl)-1-Fluorobenzene
CAS No.	26029-52-7
Molecular Formula	C7H5F3
Molecular Weight	146.11 g/mol
Synonyms	1-Fluoro-3-(difluoromethyl)benzene; 3-(Difluoromethyl)fluorobenzene; m-(Difluoromethyl)fluorobenzene; α,α-Difluoro-m-fluorotoluene; 3-Fluoro-α,α-difluorotoluene; Benzene, 1-fluoro-3-(difluoromethyl)-; (3-Fluorophenyl)difluoromethane
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethyl)-1-Fluorobenzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as strong acids and strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed and at a consistent temperature, preferably between 15-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.