Description

[5-(5-Aminoimidazol-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methoxyphosphonic Acid is a high-purity, specialized nucleoside analog intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleotide metabolism. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of next-generation therapeutics, where precise molecular structure and high chemical purity are critical for successful biological activity and regulatory approval.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis pathways.
• Proteomics & Molecular Biology: Employed in the development of labeled probes or tools for studying cellular processes and gene expression.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	[5-(5-Aminoimidazol-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methoxyphosphonic Acid
CAS No.	25635-88-5
Molecular Formula	C9H14N3O7P
Molecular Weight	307.20 g/mol
Synonyms	5-(5-Amino-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl methoxyphosphonic acid; 1-(5-Aminoimidazol-1-yl)-1,4-dideoxy-1,4-imino-D-ribitol 5-(Methylphosphonate); Aminoimidazole Nucleoside Phosphonate Analog; 5-Aminoimidazole Riboside Phosphonic Acid Derivative; 25635-88-5; (2R,3S,4R)-5-(5-Amino-1H-imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl methylphosphonate
EINECS	Contact for details

Quality Control

Our [5-(5-Aminoimidazol-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methoxyphosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.