Description

Clindamycin Palmitate Hydrochloride is a water-soluble hydrochloride salt of the palmitate ester prodrug of the lincosamide antibiotic clindamycin. This form is critical for enhancing the stability and bioavailability of the active pharmaceutical ingredient in oral dosage formulations. It is primarily used by pharmaceutical manufacturers in the production of pediatric suspensions and other oral antibiotic medications to treat serious anaerobic bacterial infections.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient in the manufacture of oral antibiotic suspensions, particularly for pediatric use.
• Antibiotic Formulations: Key intermediate in producing finished dosage forms targeting anaerobic bacteria, including those causing bone, joint, and respiratory tract infections.
• Prodrug Synthesis: Serves as a vital prodrug form of clindamycin, designed to mask the bitter taste and improve patient compliance, especially in liquid formulations.
• Research & Development: Used in microbiological research and the development of new antimicrobial agents and combination therapies.
• Veterinary Medicine: Employed in the formulation of antibacterial treatments for animals.

Basic Information

Product Name	Clindamycin Palmitate Hydrochloride
CAS No.	25507-04-4
Molecular Formula	C34H63ClN2O6S • HCl
Molecular Weight	699.86 g/mol
Synonyms	Clindamycin Palmitate HCl; Clindamycin 3-Palmitate Hydrochloride; 7(S)-Chloro-7-deoxylincomycin 3-palmitate hydrochloride; Dalacin C Palmitate; Cleocin Palmitate Hydrochloride; U-28508; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide; 3-Palmitoylclindamycin Hydrochloride
EINECS	Contact for details

Quality Control

Our Clindamycin Palmitate Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological quality is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.