Description

Sodium Camptothecin is the water-soluble sodium salt form of the potent topoisomerase I inhibitor, Camptothecin. This compound is critical for pharmaceutical research and development, particularly in the formulation of injectable anticancer therapies. It is primarily utilized by pharmaceutical manufacturers, biotechnology research firms, and academic institutions engaged in oncology drug discovery and preclinical studies.

Application

• Active Pharmaceutical Ingredient (API) for injectable anticancer formulations.
• Reference Standard in analytical chemistry and quality control laboratories for drug testing.
• Biochemical Research for studying topoisomerase I inhibition mechanisms and apoptosis.
• Preclinical Development of novel chemotherapeutic agents and combination therapies.
• Pharmaceutical Intermediates for the synthesis of more complex camptothecin analogs like irinotecan and topotecan.

Basic Information

Product Name	Sodium Camptothecin
CAS No.	25387-67-1
Molecular Formula	C20H16N2NaO5
Molecular Weight	387.34 g/mol
Synonyms	Camptothecin Sodium Salt; Camptothecin, Sodium Salt; Sodium (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione-11-carboxylate; CPT-Na; NSC 100880 (sodium salt); (S)-(+)-Camptothecin Sodium Salt; 20(S)-Camptothecin Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium Camptothecin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and development purposes. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.