Description

(7S,13E,16S,18R,19E,21R)-7-Acetoxy-18,21-Dihydroxy-16,18-Dimethyl-10-Phenyl[11]Cytochalasa-6(12),13,19-Triene-1,17-Dione is a complex, high-purity cytochalasan compound of significant interest in advanced biochemical and pharmacological research. This molecule matters as a potent and specific modulator of actin polymerization and cellular dynamics, serving as a critical tool for studying cytoskeletal function and signal transduction pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in cell biology, cancer research, and the development of novel therapeutic agents.

Application

• Biochemical Research: As a potent actin polymerization inhibitor for studying cytoskeletal architecture, cell motility, and intracellular transport mechanisms.
• Pharmacological Studies: Investigation of cellular signaling pathways, apoptosis induction, and the development of potential anti-cancer or anti-metastatic agents.
• Cell Biology Tool: Used to disrupt microfilament networks in experiments to understand cell division, morphology, and adhesion processes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories studying cytochalasins.
• Drug Discovery: A key intermediate or lead compound in the synthesis and screening of novel bioactive molecules targeting the cytoskeleton.
• Academic Research: Fundamental research in universities and institutes exploring the role of actin in various disease models and biological functions.

Basic Information

Product Name	(7S,13E,16S,18R,19E,21R)-7-Acetoxy-18,21-Dihydroxy-16,18-Dimethyl-10-Phenyl[11]Cytochalasa-6(12),13,19-Triene-1,17-Dione
CAS No.	25367-05-9
Molecular Formula	C32H37NO7
Molecular Weight	547.65 g/mol
Synonyms	Cytochalasin H; Deoxaphomin; NSC 357757; Phomin; [11]Cytochalasa-6(12),13,19-triene-1,17-dione, 7-(acetyloxy)-18,21-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E,21R)-; 7-Acetoxycytochalasin H; Antibiotic 24145
EINECS	Contact for details

Quality Control

Our (7S,13E,16S,18R,19E,21R)-7-Acetoxy-18,21-Dihydroxy-16,18-Dimethyl-10-Phenyl[11]Cytochalasa-6(12),13,19-Triene-1,17-Dione is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and other relevant tests. A detailed Certificate of Analysis (COA) documenting identity, purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.