Description

3-(Trifluoromethyl)Quinoline is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its ability to introduce the metabolically stable and lipophilic trifluoromethyl group into complex molecular architectures, significantly altering physicochemical properties. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients, agrochemicals, and specialty materials where fluorine substitution is critical for performance.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profile.
• Material Science: Used in the creation of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Research: Versatile reagent for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry: Serves as a model compound for studying fluorination reactions and the behavior of fluorinated aromatics.

Basic Information

Product Name	3-(Trifluoromethyl)Quinoline
CAS No.	25199-76-2
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	3-Trifluoromethylquinoline; Quinoline, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)chinolin; 3-TFMQ; γ-(Trifluoromethyl)quinoline; 3-CF3-Quinoline; 3-Trifluoromethyl-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.