Description

3-Fluorophenethyl Bromide is a versatile and high-value organobromine building block essential for advanced organic synthesis. Its reactive benzyl bromide moiety, activated by the electron-withdrawing fluorine substituent, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the production of novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Negishi couplings to form biaryl structures.
• Ligand & Catalyst Development: Employed in the preparation of specialized phosphine or nitrogen-based ligands for asymmetric catalysis.
• Chemical Biology Probes: Used to incorporate fluorinated phenethyl groups into molecules for studying protein-ligand interactions and metabolic pathways.

Basic Information

Product Name	3-Fluorophenethyl Bromide
CAS No.	25017-13-4
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-(2-Bromoethyl)-3-fluorobenzene; 2-(3-Fluorophenyl)ethyl Bromide; 3-Fluorophenylethyl Bromide; (3-Fluorophenyl)ethyl Bromide; β-Bromo-3-fluoroethylbenzene; 3-Fluoro-β-bromoethylbenzene; 3-Fluorobenzeneethanamine, N-bromo derivative (related); 3-Fluorophenethylbromide
EINECS	Contact for details

Quality Control

Our 3-Fluorophenethyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by GC/HPLC), identity confirmation (by IR, NMR), and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO 9001 standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.45 g/cm³
Refractive Index	~1.535

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.