Description

2-Bromobenzylsulfonyl Chloride is a versatile and reactive organosulfur compound that serves as a key synthetic intermediate in advanced organic synthesis. Its value lies in its ability to act as a sulfonylation reagent and a building block for introducing the 2-bromobenzylsulfonyl functional group into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or requiring specific sulfonamide functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the bromobenzyl moiety can contribute to biological activity.
• Material Science Research: Employed in the creation of specialty polymers, ligands for catalysis, and advanced organic materials with tailored properties.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes and activity-based protein profiling (ABPP) reagents to study biological systems.
• Sulfonamide Library Synthesis: A key reagent for the parallel and combinatorial synthesis of diverse sulfonamide compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromobenzylsulfonyl Chloride
CAS No.	24974-74-1
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	α-Bromo-o-toluenesulfonyl chloride; (2-Bromophenyl)methanesulfonyl chloride; 2-Bromobenzylsulfonyl chloride; 1-(Bromomethyl)-2-(chlorosulfonyl)benzene; o-Bromobenzylsulfonyl chloride; 2-Bromobenzenemethanesulfonyl chloride; Bromobenzylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromobenzylsulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.