Description

Harmol Glucuronide is a specific conjugated metabolite of harmol, formed via glucuronidation. This compound is of significant value as a key reference standard and analytical tool in pharmaceutical and biochemical research. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors for metabolism studies, method development, and analytical validation.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of harmol metabolites in drug development and bioanalysis.
• Metabolite Profiling & Pharmacokinetics: Essential for studying the metabolic pathways, bioavailability, and clearance rates of harmol and related β-carboline compounds.
• Enzyme Activity Assays: Serves as a specific substrate or product for investigating the activity of UDP-glucuronosyltransferase (UGT) enzymes.
• Biomarker Research: Employed in clinical and preclinical studies to understand exposure and metabolic fate.
• Analytical Method Development: A critical component for developing and validating HPLC, LC-MS, or other chromatographic methods for metabolite detection.
• Quality Control (QC) Testing: Used in QC laboratories to ensure the accuracy and reliability of analytical procedures for metabolite analysis.

Basic Information

Product Name	Harmol Glucuronide
CAS No.	24757-60-6
Molecular Formula	C17H18N2O7
Molecular Weight	362.34 g/mol
Synonyms	Harmol 7-O-β-D-Glucuronide; 1-Methyl-9H-pyrido[3,4-b]indol-7-yl β-D-Glucopyranosiduronic Acid; 7-Hydroxy-1-methyl-9H-β-carboline Glucuronide; Harmol β-D-Glucuronide; Harmol Glucuronide Conjugate; 1-Methyl-7-β-D-glucopyranuronosyloxy-β-carboline
EINECS	Contact for details

Quality Control

Our Harmol Glucuronide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) containing batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.