Description

Aspirin-Acyl--D-Glucuronide is a key metabolite of acetylsalicylic acid (aspirin), formed via glucuronidation. This compound is of significant value for researchers and manufacturers in the pharmaceutical and life sciences sectors, serving as a critical reference standard and analytical tool. It is primarily needed by professionals in drug metabolism and pharmacokinetics (DMPK) studies, analytical method development, and quality control laboratories for ensuring the accuracy of bioanalytical data.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification of aspirin metabolites in biological matrices.
• Drug Metabolism & Pharmacokinetics (DMPK): Essential for studying the metabolic pathways, bioavailability, and clearance of acetylsalicylic acid.
• Bioanalytical Method Development: Serves as a critical standard for developing and validating HPLC, LC-MS, and GC-MS assays in clinical and preclinical research.
• Toxicology Studies: Employed in research to understand the distribution and excretion profiles of aspirin and its related compounds.
• Biochemical Research: Used as a substrate or inhibitor in studies involving glucuronosyltransferase enzymes.
• Quality Control & Assurance: Acts as a benchmark for ensuring the purity and identity of aspirin-related compounds in pharmaceutical manufacturing.

Basic Information

Product Name	Aspirin-Acyl--D-Glucuronide
CAS No.	24719-72-0
Molecular Formula	C16H18O10
Molecular Weight	370.31 g/mol
Synonyms	O-Acetylsalicyloyl-β-D-glucopyranosiduronic Acid; Acetylsalicyloyl Glucuronide; Aspirin Acyl Glucuronide; ASA-Glucuronide; 2-(Acetyloxy)benzoic acid β-D-glucopyranosiduronic acid ester; 2-Acetoxybenzoyl-β-D-glucuronide; Salicyloyl Acetyl Glucuronide; AAG
EINECS	Contact for details

Quality Control

Our Aspirin-Acyl--D-Glucuronide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and reference materials. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.