Description

Ethynylestradiol-3-Sulfate is a sulfated metabolite of the synthetic estrogen ethinylestradiol. This compound is of significant value as a key reference standard and analytical marker in pharmaceutical research and development. It is primarily utilized by professionals in the pharmaceutical, biotechnology, and clinical diagnostics industries for method development, quality control, and metabolic studies related to steroidal drugs.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the quantification and identification of ethinylestradiol metabolites in drug formulations and biological matrices.
• Metabolic Pathway Research: Essential for studying the sulfation metabolic pathways of synthetic estrogens in pharmacokinetic and pharmacodynamic studies.
• Bioanalytical Method Development: Serves as a critical calibrant in developing and validating HPLC, LC-MS, and GC-MS methods for steroid analysis.
• Quality Control (QC) Testing: Employed in pharmaceutical QC laboratories to ensure the purity and consistency of active pharmaceutical ingredients (APIs) and finished products.
• Clinical Diagnostics: Used in the development of diagnostic assays to monitor hormone levels and metabolic profiles.
• Academic & Institutional Research: Supports fundamental research in endocrinology, steroid chemistry, and toxicology at universities and research institutes.

Basic Information

Item	Details
Product Name	Ethynylestradiol-3-Sulfate
CAS No.	24560-70-1
Molecular Formula	C20H24O5S
Molecular Weight	376.47 g/mol
Synonyms	Ethinyl Estradiol 3-Sulfate; EE2-3-Sulfate; 17α-Ethynylestradiol 3-Sulfate; 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol 3-Sulfate; Ethynylestradiol Sulfate; NSC 10973; 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-Sulfate
EINECS	Contact for details

Quality Control

Our Ethynylestradiol-3-Sulfate is manufactured and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.