Description

o-Nicotine CAS NO 23950-04-1 is a specific positional isomer of nicotine, a naturally occurring alkaloid. This high-purity chemical intermediate is critical for advanced research and synthesis in medicinal chemistry and agrochemical development. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and analytical reference standard producers seeking precise molecular tools for innovation.

Application

• Pharmaceutical Research & Development: A key chiral intermediate and building block for synthesizing novel nicotine analogs and other bioactive alkaloids for pharmacological studies.
• Agrochemical Synthesis: Used in the development and production of next-generation neonicotinoid insecticides and other crop protection agents.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for method development, calibration, and quality control in analytical laboratories (e.g., HPLC, GC-MS).
• Biochemical Studies: Employed in neuroscience and receptor-binding research to study nicotinic acetylcholine receptors (nAChRs) and related neurological pathways.
• Chemical Synthesis: A versatile precursor for the synthesis of more complex heterocyclic compounds and specialty fine chemicals.

Basic Information

Product Name	o-Nicotine
CAS No.	23950-04-1
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(S)-3-(1-Methyl-2-pyrrolidinyl)pyridine; (S)-Nicotine; (-)-Nicotine; L-Nicotine; (S)-(-)-Nicotine; 1-Methyl-2-(3-pyridyl)pyrrolidine; (S)-1-Methyl-2-(3-pyridyl)pyrrolidine
EINECS	245-952-2

Quality Control

Our o-Nicotine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific chromatographic and spectroscopic results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.