Description

Tetranorprostaglandin E1 is a potent and biologically active prostaglandin metabolite, valued for its role in advanced research and pharmaceutical development. This compound is a critical intermediate and reference standard for studying vascular biology, inflammation pathways, and renal function. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on cardiovascular and renal therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel prostaglandin-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard in analytical methods (HPLC, LC-MS) for quantifying prostaglandin metabolites in biological samples.
• Mechanistic Studies: Essential for in vitro and in vivo research on vasodilation, platelet aggregation, and inflammatory response mechanisms.
• Drug Discovery: A valuable tool for high-throughput screening and target validation in cardiovascular and renal disease research programs.
• Diagnostic Development: Employed in the calibration and development of diagnostic assays for metabolic and inflammatory disorders.

Basic Information

Product Name	Tetranorprostaglandin E1
CAS No.	23923-84-4
Molecular Formula	C₁₆H₂₈O₅
Molecular Weight	300.39 g/mol
Synonyms	13,14-Dihydro-15-keto-tetranor-PGE1; 13,14-Dihydro-15-keto-tetranor-prostaglandin E1; 11α,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid (Tetranor derivative); PGEM-I; Tetranor PGE1; Tetranor Prostaglandin E1; 15-Keto-13,14-dihydro-tetranor-PGE1
EINECS	Contact for details

Quality Control

Our Tetranorprostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.