Description

Triacetyl-β-Cyclodextrin is a chemically modified derivative of β-cyclodextrin, where hydroxyl groups are acetylated to enhance its solubility and stability in organic solvents. This modification is critical for creating stable inclusion complexes with a wide range of hydrophobic guest molecules, improving their bioavailability, stability, and controlled release. It is an essential functional excipient and complexing agent for demanding applications in the pharmaceutical, food, and cosmetic industries, where precise molecular encapsulation is required.

Application

• Pharmaceutical Formulations: As a solubility enhancer and stabilizer for poorly water-soluble active pharmaceutical ingredients (APIs) in oral, topical, and injectable drugs.
• Flavor & Fragrance Encapsulation: To protect volatile or sensitive flavor oils and fragrance compounds from oxidation, evaporation, and light degradation in food and cosmetic products.
• Analytical Chemistry: Used as a chiral stationary phase modifier in gas chromatography (GC) and capillary electrophoresis (CE) for the separation of enantiomers.
• Nutraceutical Delivery Systems: For the encapsulation of vitamins, fatty acids, and other bioactive compounds to mask taste and improve shelf-life.
• Chemical Synthesis: Acts as a phase-transfer catalyst or a molecular reactor in organic synthesis due to its hydrophobic cavity.
• Cosmetic Stabilization: To stabilize active ingredients, UV filters, and pigments in creams, lotions, and sunscreens.

Basic Information

Product Name	Triacetyl-β-Cyclodextrin
CAS No.	23739-88-0
Molecular Formula	C96H144O72
Molecular Weight	2473.14 g/mol
Synonyms	β-Cyclodextrin, triacetate; 2,3,6-Tri-O-acetyl-β-cyclodextrin; Peracetylated β-Cyclodextrin; Triacetyl-β-CD; TA-β-CD; Acetylated Beta Cyclodextrin; Heptakis(2,3,6-tri-O-acetyl)-β-cyclodextrin; Cycloheptaamylose triacetate
EINECS	Contact for details

Quality Control

Our Triacetyl-β-Cyclodextrin is manufactured under a strict quality management system. Each batch is tested to ensure it meets stringent specifications for identity, purity, and acetyl substitution degree. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay by HPLC, residual solvent levels, and moisture content. Our quality commitment supports applications requiring GMP-grade or high-purity research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent moisture absorption and caking.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Degree of Substitution (NMR)	2.8 - 3.2 (Acetyl/glucose unit)
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.