Description

Pactamycin is a potent aminocyclitol antibiotic originally isolated from *Streptomyces pactum*. This compound is of significant interest in biochemical and pharmacological research due to its unique mechanism of action, which involves the inhibition of protein synthesis in both prokaryotic and eukaryotic cells. It serves as a critical research tool for scientists in antibiotic mechanism studies, oncology research, and molecular biology, providing insights into ribosome function and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific inhibitor of protein synthesis to study ribosomal function and translation mechanisms.
• Antibiotic Research: Serves as a reference compound for investigating the structure-activity relationships of aminocyclitol antibiotics and exploring new antimicrobial strategies.
• Oncology & Cell Biology: Employed in vitro to study apoptosis, cell cycle arrest, and to probe pathways involved in cancer cell proliferation.
• Molecular Pharmacology: A tool compound for high-throughput screening and target validation in drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in microbiology and genetics.

Basic Information

Product Name	Pactamycin
CAS No.	23668-11-3
Molecular Formula	C₂₃H₃₃N₃O₈
Molecular Weight	479.52 g/mol
Synonyms	Pactamycin; Antibiotic U-15167; NSC 529835; Pactamycine; (1R,2S,3S,4R,6S)-4,6-Diamino-1,2,3-cyclohexanetriol 2,4-diacetate 6-[(3S)-3-Amino-3-deoxy-β-D-ribofuranosyl] Deriv.
EINECS	Contact for details

Quality Control

Our Pactamycin is produced and handled under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and impurity profiling. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.