Description

Heptakis-(2,3,6-Tri-O-benzoyl)-β-cyclodextrin is a highly functionalized derivative of β-cyclodextrin, where all seven primary hydroxyl groups are esterified with benzoate groups. This chemical modification significantly enhances its molecular encapsulation capabilities and solubility in organic solvents, making it a powerful chiral selector and complexing agent. It is a critical intermediate and reagent for researchers and manufacturers in advanced organic synthesis, particularly for developing enantioselective catalysts and separation media. Key industries that utilize this specialized compound include pharmaceutical development, fine chemical synthesis, and analytical chemistry for chiral resolution.

Application

• Chiral Stationary Phase (CSP) Development: A key precursor for synthesizing high-performance liquid chromatography (HPLC) columns used in the separation of enantiomers for drug purity analysis.
• Asymmetric Synthesis Catalyst: Serves as a chiral scaffold or ligand in catalytic reactions to induce enantioselectivity in the production of active pharmaceutical ingredients (APIs).
• Molecular Recognition Studies: Used in research to study host-guest chemistry, supramolecular assembly, and the design of synthetic receptors.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex cyclodextrin derivatives with tailored properties for drug delivery and formulation.
• Analytical Reference Standard: Acts as a pure standard for method development and validation in chiral analytical laboratories.
• Material Science: A building block for creating functionalized polymers and nanomaterials with specific molecular recognition sites.

Basic Information

Product Name	Heptakis-(2,3,6-Tri-O-benzoyl)-β-cyclodextrin
CAS No.	23666-43-5
Molecular Formula	C147H98O49
Molecular Weight	~2472.2 g/mol
Synonyms	Heptakis(2,3,6-tri-O-benzoyl)-β-cyclodextrin; β-Cyclodextrin, heptakis(2,3,6-tri-O-benzoyl)-; Per(2,3,6-tri-O-benzoyl)-β-cyclodextrin; 2,3,6-Tri-O-benzoyl-β-cyclodextrin; Fully benzoylated β-cyclodextrin; Heptakis-(2,3,6-Tri-o-Benzoyl)- -Cy; Benzoylated β-CD
EINECS	Contact for details

Quality Control

Our Heptakis-(2,3,6-Tri-O-benzoyl)-β-cyclodextrin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure high batch-to-batch consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in common organic solvents (e.g., DCM, Chloroform, THF)
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.