Description

Batrachotoxinin A 20-(2,4,5-Trimethyl-1H-Pyrrole-3-Carboxylate) is a highly potent and specific steroidal alkaloid derivative, serving as a crucial advanced intermediate in neurobiological and pharmacological research. Its primary value lies in its role as a precursor for the synthesis of batrachotoxin, a powerful neurotoxin used to study voltage-gated sodium channels. This compound is essential for research institutions and pharmaceutical R&D departments focused on neuroscience, toxin research, and the development of novel analgesic or anesthetic agents.

Application

• Neuroscience Research: Critical intermediate for synthesizing batrachotoxin, a tool compound for studying the mechanism and modulation of voltage-gated sodium channels in neuronal cells.
• Pharmacological Studies: Used in the research and development of novel ligands that target ion channels, aiding in the discovery of potential new classes of anesthetics, analgesics, or antiarrhythmic drugs.
• Toxicology & Venom Research: Serves as a reference standard and synthetic target in the study of natural neurotoxins, their biosynthesis, and their ecological roles.
• Chemical Biology: Employed in the design and synthesis of molecular probes to investigate ion channel structure, function, and localization within biological systems.
• Academic & Institutional R&D: Supplied to universities and government research labs for fundamental studies in biochemistry, physiology, and molecular pharmacology.

Basic Information

Product Name	Batrachotoxinin A 20-(2,4,5-Trimethyl-1H-Pyrrole-3-Carboxylate)
CAS No.	23509-21-9
Molecular Formula	C31H39NO5
Molecular Weight	505.65 g/mol
Synonyms	Batrachotoxinin A 20-(2,4,5-Trimethylpyrrole-3-carboxylate); 3-Pyrrolecarboxylic acid, 2,4,5-trimethyl-, (3β,16β)-20-ethyl-13-methyl-2,3,16,18-tetradehydro-14,19-epoxy-18,19-secobufa-4,20,22-trienolide-16-yl ester; Batrachotoxinin A 20-ester with 2,4,5-trimethyl-1H-pyrrole-3-carboxylic acid; BTX precursor; Batrachotoxin intermediate; 23509-21-9
EINECS	Contact for details

Quality Control

Our Batrachotoxinin A 20-(2,4,5-Trimethyl-1H-Pyrrole-3-Carboxylate) is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. Identity and purity are verified by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.