Description

1A,1B-Dihomo Prostaglandin E1 is a synthetic prostaglandin analog, a key intermediate in the synthesis of advanced pharmaceutical compounds. This high-purity intermediate is critical for ensuring the efficacy and consistency of final active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of prostaglandin-based APIs and other bioactive molecules.
• Biochemical Research: Used as a reference standard and reagent in studies investigating prostaglandin pathways, receptor binding, and cellular signaling mechanisms.
• Drug Discovery & Development: Serves as a key starting material or intermediate in medicinal chemistry programs targeting inflammation, cardiovascular function, and ocular health.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials and commercial drug substances.

Basic Information

Product Name	1A,1B-Dihomo Prostaglandin E1
CAS No.	23452-98-4
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	1a,1b-Dihomo PGE1; Dihomo Prostaglandin E1; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 1a,1b-Dihomo-PGE1; 1A,1B-Dihomo-PGE1; 1a,1b-Homo PGE1; Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11α,13E,15S)-
EINECS	Contact for details

Quality Control

Our 1A,1B-Dihomo Prostaglandin E1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of -20°C or below to prevent oxidation and ensure long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.