Description

Trichloroacetic Acid 2-Chloro-4-(Fluorosulfonyl)Phenyl Ester is a specialized organosulfur and organofluorine compound that serves as a versatile chemical intermediate. Its unique structure, featuring both a reactive sulfonyl fluoride group and an ester linkage, makes it a valuable building block for synthesizing more complex molecules in advanced research and manufacturing. This high-purity intermediate is primarily sought by the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals. Its precise reactivity profile enables targeted modifications in complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and targeted covalent inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its reactive fluorosulfonyl group.
• Chemical Research & Development: A critical reagent in medicinal chemistry and material science for introducing sulfonyl fluoride motifs, which are valuable in chemical biology and probe development.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific sulfonate ester derivatives.
• Cross-Coupling Reactions: Serves as an electrophilic coupling partner in palladium-catalyzed and other metal-mediated cross-coupling reactions to form carbon-sulfur bonds.

Basic Information

Product Name	Trichloroacetic Acid 2-Chloro-4-(Fluorosulfonyl)Phenyl Ester
CAS No.	23379-03-5
Molecular Formula	C8H3Cl4FO4S
Molecular Weight	360.94 g/mol
Synonyms	2-Chloro-4-(fluorosulfonyl)phenyl trichloroacetate; Phenyl trichloroacetate, 2-chloro-4-(fluorosulfonyl)-; 2-Chloro-4-fluorosulfonylphenyl trichloroacetate; Trichloroacetic acid 2-chloro-4-fluorosulfonylphenyl ester; (2-Chloro-4-fluorosulfonylphenyl) trichloroacetate; CAS 23379-03-5
EINECS	Contact for details

Quality Control

Our Trichloroacetic Acid 2-Chloro-4-(Fluorosulfonyl)Phenyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions, preferably with desiccant. Keep away from heat, sparks, and open flame. Store separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.