Description

Leurosine is a naturally occurring alkaloid compound derived from the Madagascar periwinkle plant (*Catharanthus roseus*). This molecule is of significant interest in pharmaceutical research due to its complex structure and biological activity profile. It serves as a critical intermediate and reference standard for the development and quality control of oncology-related pharmaceuticals. Key industries requiring this compound include pharmaceutical R&D, academic research institutions, and analytical laboratories focused on natural product chemistry and anticancer drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the identification and quantification of vinca alkaloids in drug substances and finished products.
• Oncology Research: Serves as a key biochemical tool and intermediate in the study of tubulin binding mechanisms and the development of novel antimitotic agents.
• Natural Product Isolation & Synthesis: Acts as a target molecule for synthetic organic chemists and a marker compound for the quality assessment of plant extracts.
• Analytical Method Development: Employed in the validation of chromatographic methods (HPLC, LC-MS) for the analysis of complex alkaloid mixtures.
• Biochemical Assays: Utilized in *in vitro* studies to investigate cell cycle arrest and apoptosis in various cancer cell lines.

Basic Information

Product Name	Leurosine
CAS No.	23360-92-1
Molecular Formula	C46H56N4O9
Molecular Weight	809.0 g/mol
Synonyms	Vincaleukoblastine, 3',4'-Didehydro-4'-deoxyvincaleukoblastine; NSC 90636; Leurosine sulfate; Catharanthus roseus alkaloid; Vincoleuroblastine
EINECS	Contact for details

Quality Control

Every batch of Leurosine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.