Description

Gw9662 is a potent and selective peroxisome proliferator-activated receptor gamma (PPARγ) antagonist used extensively in biochemical and pharmacological research. This compound is critical for studying adipocyte differentiation, insulin sensitization, and inflammatory pathways. It serves as an essential tool for researchers and pharmaceutical developers in the fields of metabolic disease, diabetes, and cancer research, where modulating PPARγ activity is a key investigative strategy.

Application

• Primary research tool for studying PPARγ receptor function and signal transduction pathways.
• Investigation of adipogenesis (fat cell formation) and its role in metabolic disorders.
• Pharmacological studies targeting insulin resistance and type 2 diabetes mechanisms.
• Exploration of anti-inflammatory effects and applications in inflammatory disease models.
• Cell-based assays for drug discovery and screening in metabolic and oncological research.
• Academic and industrial R&D for developing novel therapeutic agents targeting nuclear receptors.

Basic Information

Product Name	Gw9662
CAS No.	22978-25-2
Molecular Formula	C17H14N2O3S
Molecular Weight	326.37 g/mol
Synonyms	GW-9662; GW 9662; 2-Chloro-5-nitro-N-phenylbenzamide; PPARγ Antagonist GW9662; PPARγ Inhibitor; T0070907 analog; Bisphenol A diglycidyl ether (common mis-association, included for clarity); PPARG antagonist
EINECS	Contact for details

Quality Control

Our Gw9662 is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC chromatograms and NMR spectra. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee it meets the stringent requirements of pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.