Description

2-Chloro-5-Trifluoromethylbenzyl Chloride is a versatile and highly reactive halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the trifluoromethyl and chlorine substituents, which are key motifs for modulating the physicochemical and biological properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring trifluoromethylated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the chloro and trifluoromethyl groups contribute to efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving diverse R&D and scale-up projects.
• Polymer Modification: Can be utilized to introduce functional benzyl groups into polymer chains, altering material properties.

Basic Information

Product Name	2-Chloro-5-Trifluoromethylbenzyl Chloride
CAS No.	22902-94-9
Molecular Formula	C8H5Cl2F3
Molecular Weight	243.03 g/mol
Synonyms	1-(Chloromethyl)-2-chloro-5-(trifluoromethyl)benzene; α,2-Dichloro-α-(trifluoromethyl)toluene; 2-Chloro-α-(chloromethyl)-α,α,α-trifluorotoluene; 2-Chloro-5-(trifluoromethyl)benzyl Chloride; Benzene, 1-(chloromethyl)-2-chloro-5-(trifluoromethyl)-; (2-Chloro-5-trifluoromethylphenyl)methyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Trifluoromethylbenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for fine chemical synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Handle and store under an inert atmosphere if prolonged storage is required to minimize potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.