Description

2-Butyl-1,3,4-Trifluorobenzene is a fluorinated aromatic compound of significant interest in advanced organic synthesis. Its value lies in its role as a versatile building block for introducing trifluoromethylphenyl motifs into complex molecular architectures. This specialty intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• As a key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Utilized in agrochemical research for creating novel herbicides, fungicides, and insecticides where the fluorine atoms contribute to biological activity and environmental persistence.
• Serves as a precursor in material science for developing specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Employed in organic synthesis laboratories as a versatile reagent for cross-coupling reactions, nucleophilic aromatic substitution, and other fluorobenzene chemistry.
• Acts as a standard or reference compound in analytical chemistry for method development and calibration in chromatographic systems.

Basic Information

Product Name	2-Butyl-1,3,4-Trifluorobenzene
CAS No.	22872-43-1
Molecular Formula	C₁₀H₁₁F₃
Molecular Weight	188.19 g/mol
Synonyms	1,3,4-Trifluoro-2-butylbenzene; 2-Butyl-1,3,4-trifluorobenzene; 1-Butyl-2,3,6-trifluorobenzene; Butyltrifluorobenzene; 22872-43-1; Benzene, 2-butyl-1,3,4-trifluoro-; 2-n-Butyl-1,3,4-trifluorobenzene
EINECS	Contact for details

Quality Control

Our 2-Butyl-1,3,4-Trifluorobenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.15 g/mL
Refractive Index (n20D)	~1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.