Description

3-(5-Fluoro-Pyridin-3-Yl)-Propionic Acid is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a fluorinated heterocycle, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its conjugated system.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	3-(5-Fluoro-Pyridin-3-Yl)-Propionic Acid
CAS No.	22620-28-6
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	3-(5-Fluoropyridin-3-yl)propanoic acid; 5-Fluoro-3-pyridinepropionic Acid; 3-(5-Fluoro-3-pyridinyl)propanoic Acid; β-(5-Fluoro-3-pyridyl)propionic Acid; 22620-28-6; 3-Pyridinepropanoic acid, 5-fluoro-; 5-Fluoro-3-pyridinepropanoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(5-Fluoro-Pyridin-3-Yl)-Propionic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.