Description

7-Chloro-1,6,7,8-Tetradeoxy-6-[[[(2S)-1-Methyl-4β-Propyl-2α-Pyrrolidinyl]Carbonyl]Amino]-1-(Methylsulfinyl)-α-L-Threo-D-Galacto-Octopyranose is a complex, high-purity chemical intermediate with a defined stereochemistry, crucial for advanced synthetic pathways. Its value lies in its role as a sophisticated building block for the research and development of novel pharmaceutical compounds, particularly in the area of glycosidase inhibitors and carbohydrate-based therapeutics. This product is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require precise molecular tools for creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential new chemical entities (NCEs) and active pharmaceutical ingredients (APIs), especially for metabolic and infectious disease targets.
• Glycosidase Inhibitor Research: Serves as a core structural component for developing novel inhibitors that modulate carbohydrate-processing enzymes, with applications in antiviral, anticancer, and metabolic disorder research.
• Carbohydrate Chemistry: Used in advanced studies of glycosylation reactions, oligosaccharide synthesis, and the exploration of structure-activity relationships (SAR) in complex sugar derivatives.
• Bioconjugation & Probe Development: Acts as a specialized precursor for creating labeled probes or conjugates used in biochemical assays and diagnostic research.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of advanced therapeutic candidates.

Basic Information

Product Name	7-Chloro-1,6,7,8-Tetradeoxy-6-[[[(2S)-1-Methyl-4β-Propyl-2α-Pyrrolidinyl]Carbonyl]Amino]-1-(Methylsulfinyl)-α-L-Threo-D-Galacto-Octopyranose
CAS No.	22431-46-5
Molecular Formula	C₁₉H₃₅ClN₂O₆S
Molecular Weight	454.99 g/mol
Synonyms	7-Chloro-1,6,7,8-tetradeoxy-6-[[[(2S)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-(methylsulfinyl)-α-L-threo-D-galacto-octopyranose; (2S,3S,4R,5S,6S)-7-Chloro-6-[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-(methylsulfinyl)-2,3,4,5,6-pentahydroxyheptane; CAS 22431-46-5; A complex chlorinated deoxy amino sugar derivative; Methylsulfinyl galacto-octopyranose derivative; Pyrrolidinylcarbonyl amino sugar.
EINECS	Contact for details

Quality Control

Our 7-Chloro-1,6,7,8-Tetradeoxy-6-[[[(2S)-1-Methyl-4β-Propyl-2α-Pyrrolidinyl]Carbonyl]Amino]-1-(Methylsulfinyl)-α-L-Threo-D-Galacto-Octopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.