Description

2H-1-Benzopyran-6-Ol, 3,4-Dihydro-2,7,8-Trimethyl-2-[(4R,8R)-4,8,12-Trimethyltridecyl]-, 6-Acetate, (2R)- is a high-purity, synthetically derived tocopherol acetate derivative, specifically the acetate ester of (2R)-α-tocopherol. This compound is valued for its potent antioxidant properties and enhanced stability compared to its free phenol form, making it a critical ingredient in formulations requiring long-term oxidative protection. It is primarily sought after by manufacturers in the pharmaceutical, nutraceutical, and high-end cosmetic industries for its role in stabilizing sensitive actives and delivering vitamin E activity.

Application

• Pharmaceutical Formulations: Used as an antioxidant stabilizer in injectable solutions, soft gelatin capsules, and topical ointments to prevent degradation of active pharmaceutical ingredients (APIs).
• Nutraceutical & Dietary Supplements: A key active ingredient in vitamin E supplements, multivitamin complexes, and functional foods for its nutritional and antioxidant benefits.
• Cosmetics & Personal Care: Incorporated into anti-aging serums, sunscreens, moisturizers, and hair care products to protect formulations from rancidity and provide skin-conditioning benefits.
• Animal Feed & Nutrition: Employed as a vitamin E source and preservative in premixes and finished feed to support animal health and prevent oxidation of fats.
• Food Fortification: Used to fortify edible oils, margarines, and dairy alternatives to improve nutritional profile and shelf-life.
• Research & Development: Serves as a high-purity reference standard and biochemical reagent in life science research, particularly in studies of oxidative stress and lipid metabolism.

Basic Information

Product Name	2H-1-Benzopyran-6-Ol, 3,4-Dihydro-2,7,8-Trimethyl-2-[(4R,8R)-4,8,12-Trimethyltridecyl]-, 6-Acetate, (2R)-
CAS No.	22373-06-4
Molecular Formula	C31H52O3
Molecular Weight	472.75 g/mol
Synonyms	(2R)-α-Tocopherol Acetate; D-α-Tocopherol Acetate; Vitamin E Acetate (natural form); (R,R,R)-α-Tocopheryl Acetate; 2R,4'R,8'R-α-Tocopherol Acetate; 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate; all-rac-α-Tocopherol Acetate (mixture); E307
EINECS	244-907-0

Quality Control

Our (2R)-α-Tocopherol Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency. We provide Certificates of Analysis (COA) that detail results for assay, optical rotation, and impurity profiles, ensuring traceability and compliance with relevant pharmacopoeial standards (e.g., USP, Ph. Eur.) where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, maintaining an inert atmosphere (e.g., under nitrogen) in the headspace of the container is recommended to preserve stability and potency.

Specification

Item	Specification
Appearance	Clear, pale yellow to yellow viscous oil
Identification (IR)	Conforms to reference spectrum
Specific Optical Rotation [α]20/D	+24.0° to +28.0°
Assay (HPLC)	≥ 96.0% (as C31H52O3)
Related Substances (HPLC)	Total impurities ≤ 4.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.