Description

3-Fluoro-4-Hydroxypyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique electronic properties conferred by the fluorine atom and hydroxyl group, which make it an essential intermediate for creating complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its fluorine moiety for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a chelating agent or a structural component in designing metal-organic frameworks (MOFs) and homogeneous catalysts.
• Material Science Research: Building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and fluorescent tags for biochemical and diagnostic applications.

Basic Information

Product Name	3-Fluoro-4-Hydroxypyridine
CAS No.	22282-73-1
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	4-Hydroxy-3-fluoropyridine; 3-Fluoro-4-pyridinol; 3-Fluoro-4-pyridinone (tautomer); 3-Fluoro-4(1H)-pyridinone; 3-Fluoropyridin-4-ol; 4-Pyridinol, 3-fluoro-; 3-Fluoro-4-hydroxypyridine; 3-Fluoro-4-pyridinol
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.