Description

5-Trifluoromethyl-Pyridine-2-Carboxylic Acid Amide is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique trifluoromethyl-substituted pyridine core offers exceptional metabolic stability and lipophilicity, making it indispensable for creating advanced functional molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials that require specific thermal and chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	5-Trifluoromethyl-Pyridine-2-Carboxylic Acid Amide
CAS No.	22245-86-9
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	2-Pyridinecarboxamide, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)picolinamide; 5-Trifluoromethylpicolinamide; 5-Trifluoromethyl-2-pyridinecarboxamide; 5-Trifluoromethyl-2-carbamoylpyridine; 2-Carbamoyl-5-(trifluoromethyl)pyridine; 5-Trifluoromethylpyridine-2-carboxamide; Amide of 5-Trifluoromethylpicolinic Acid
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-Pyridine-2-Carboxylic Acid Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your regulatory needs in R&D and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.