Description

2-Hydroxy-3-Trifluoromethylpyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a hydroxyl group with a trifluoromethyl substituent on the pyridine ring, makes it indispensable for introducing specific physicochemical properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials due to its fluorine content.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2-Hydroxy-3-Trifluoromethylpyridine
CAS No.	22245-83-6
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	3-(Trifluoromethyl)pyridin-2-ol; 2-Pyridinol, 3-(trifluoromethyl)-; 3-Trifluoromethyl-2-pyridinol; 2-Hydroxy-3-(trifluoromethyl)pyridine; 2(1H)-Pyridinone, 3-(trifluoromethyl)-; α,α,α-Trifluoro-2-hydroxy-3-picoline
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Trifluoromethylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.