Description

2,5-Dichloro-4-Hydroxybenzenesulfonyl Fluoride is a versatile and reactive sulfonyl fluoride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a sulfonyl fluoride and a phenolic hydroxyl group, makes it a valuable precursor for constructing complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for sulfonamide-based drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Used in activity-based protein profiling (ABPP) and covalent inhibitor design due to the reactive sulfonyl fluoride group.
• Polymer & Material Science: Monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical resistance.
• Dyestuff & Pigment Intermediate: Used in the synthesis of complex dyes and high-performance pigments.
• Custom Synthesis & R&D: Serves as a starting material for contract research organizations and fine chemical companies developing proprietary compounds.

Basic Information

Product Name	2,5-Dichloro-4-Hydroxybenzenesulfonyl Fluoride
CAS No.	22243-90-9
Molecular Formula	C6H3Cl2FO3S
Molecular Weight	245.06 g/mol
Synonyms	4-Hydroxy-2,5-dichlorobenzenesulfonyl Fluoride; 2,5-Dichloro-4-hydroxybenzenesulfonic acid fluoride; 2,5-Dichloro-4-hydroxybenzene-1-sulfonyl fluoride; Benzenesulfonyl fluoride, 2,5-dichloro-4-hydroxy-; 2,5-Dichloro-4-hydroxy phenylsulfonyl fluoride; 2,5-Dichloro-4-hydroxyphenylsulfonyl fluoride; 2,5-Dichloro-4-phenolsulfonyl fluoride
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-Hydroxybenzenesulfonyl Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.