Description

(+/-)-Vesamicol Hydrochloride CAS NO 22232-64-0 is a potent and selective inhibitor of the vesicular acetylcholine transporter (VAChT), making it a critical pharmacological tool for neuroscience research. Its primary value lies in its ability to modulate cholinergic neurotransmission, which is fundamental to studying cognitive function, memory, and neurodegenerative diseases. This compound is essential for researchers and pharmaceutical developers in the fields of neuropharmacology, biochemistry, and the development of treatments for conditions like Alzheimer's disease.

Application

• Neuroscience Research: A key tool compound for studying the cholinergic system, synaptic vesicle function, and neurotransmitter release mechanisms.
• Pharmacological Studies: Used to investigate the role of acetylcholine in learning, memory, and cognitive processes in vitro and in vivo.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel therapeutics for neurodegenerative disorders.
• Biochemical Assays: Employed in high-throughput screening and functional assays to identify and characterize new VAChT inhibitors or modulators.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research into neurotransmission and neurochemistry.

Basic Information

Product Name	(+/-)-Vesamicol Hydrochloride
CAS No.	22232-64-0
Molecular Formula	C20H28ClNO
Molecular Weight	333.90 g/mol
Synonyms	trans-2-(4-Phenylpiperidino)cyclohexanol hydrochloride; AH-5183; (±)-Vesamicol HCl; Vesamicol (racemic) hydrochloride; VAChT Inhibitor; trans-2-(4-Phenyl-1-piperidinyl)cyclohexanol hydrochloride; 1-(1-Phenyl-4-piperidyl)cyclohexan-2-ol hydrochloride (racemate)
EINECS	Contact for details

Quality Control

Our (+/-)-Vesamicol Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible results for our global clientele in academia and pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.