Description

DL-PGE2 (CAS NO 22230-04-2) is a synthetic prostaglandin E2 derivative, a key bioactive lipid mediator involved in numerous physiological processes. Its primary value lies in its utility as a critical reference standard and research chemical for studying inflammatory pathways, reproductive biology, and cellular signaling. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and diagnostic manufacturers focused on developing novel therapeutics and analytical methods.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, GC-MS) of prostaglandin-based drugs and metabolites.
• Biochemical Research: Serves as a crucial tool for investigating the role of prostaglandin E2 in inflammation, pain, fever, and smooth muscle contraction.
• Cell Culture & In Vitro Studies: Applied in studies of ovulation, uterine contraction, and cervical ripening in reproductive biology research.
• Diagnostic Kit Development: Utilized as a calibrant or component in the development of immunoassays (ELISA) for prostaglandin detection.
• Signal Transduction Studies: Acts as a ligand to study EP receptor (EP1-EP4) activation and downstream cAMP or calcium signaling pathways.
• Quality Control: Employed by manufacturers to ensure the purity and potency of prostaglandin-related pharmaceutical ingredients.

Basic Information

Product Name	DL-PGE2
CAS No.	22230-04-2
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	Dinoprostone; Prostaglandin E2 (Racemate); PGE2; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid; U-12062; Prostin E2
EINECS	244-856-8

Quality Control

Our DL-PGE2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.