Description

Cytochalasin C is a potent fungal metabolite belonging to the cytochalasin family, known for its specific ability to disrupt actin polymerization in eukaryotic cells. This compound is a critical research tool for studying cytoskeletal dynamics, cell motility, and membrane trafficking processes. It is primarily utilized by researchers in cell biology, pharmacology, and toxicology for in vitro studies and biochemical assays.

Application

• Cell Biology Research: Used as a specific inhibitor of actin filament assembly to study cell shape, division, and motility.
• Cytoskeletal Studies: Essential for investigating the role of the actin cytoskeleton in cellular processes like endocytosis and cytokinesis.
• Pharmacological Research: Employed in assays to screen for compounds that interact with or modulate the actin cytoskeleton.
• Toxicology Studies: Serves as a model compound to understand the effects of mycotoxins on cellular structures and functions.
• Biochemical Reagent: Used in the preparation of cell extracts and in experiments requiring the arrest of actin-dependent processes.

Basic Information

Product Name	Cytochalasin C
CAS No.	22144-76-9
Molecular Formula	C30H37NO6
Molecular Weight	507.62 g/mol
Synonyms	Cytochalasin C; NSC 209802; Phomin; (3S,6S,7R,16R,18E)-6,7-Epoxy-18,19-didehydro-4,5,6,7,16,17-hexahydro-3-hydroxy-16-methyl-1H-2-benzoxacyclooctadecine-1,9(4H)-dione; 10-Phenyl-[11]cytochalasan-6,21-dione, 7,20-epoxy-1,16,18-trihydroxy-; Zygosporin A (related compound)
EINECS	Contact for details

Quality Control

Our Cytochalasin C is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.