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Bromoacetylcholine Bromide Inhibitor Of Choline CAS NO 22004-27-9


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CAS No.:22004-27-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bromoacetylcholine Bromide Inhibitor Of Choline is a specialized biochemical tool compound, a potent and selective irreversible inhibitor of choline acetyltransferase (ChAT). This compound is critical for researchers investigating the cholinergic system, which is fundamental to neurological function and a key target in various disease studies. It is primarily utilized in neuroscience, pharmacology, and biochemistry research for enzyme inhibition studies, mechanism of action investigations, and the development of experimental models for neurodegenerative conditions.

Application

  • Neuroscience Research: Used as a key reagent to inhibit acetylcholine synthesis, enabling the study of cholinergic neurotransmission, synaptic plasticity, and related neurological pathways.
  • Pharmacological Studies: Employed in in vitro and ex vivo assays to evaluate the effects of cholinergic system disruption, aiding in drug discovery for neurological disorders.
  • Biochemical Enzyme Analysis: Serves as a specific active-site directed irreversible inhibitor for choline acetyltransferase (ChAT), facilitating enzyme kinetics and structural studies.
  • Model Development: Utilized to create experimental models of cholinergic deficiency, which are relevant for research on Alzheimer's disease, myasthenia gravis, and other conditions.
  • Academic & Institutional Research: A fundamental tool in university and institutional labs for graduate-level and post-doctoral research projects focused on neurochemistry.

Basic Information

Product Name Bromoacetylcholine Bromide Inhibitor Of Choline
CAS No. 22004-27-9
Molecular Formula C7H15Br2NO2
Molecular Weight 305.01 g/mol
Synonyms (2-Bromoacetyl)choline Bromide; Bromoacetylcholine Bromide; Choline, (bromoacetyl)-, bromide; Bromoacetylcholine; 2-Bromoacetylcholine Bromide; BACB; NSC 32623; ChAT Inhibitor
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Quality Control

Our Bromoacetylcholine Bromide is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals, ensuring reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals < 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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