Description

2-Amino-5-Fluoropyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a fluorine atom on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination reactions and heterocyclic chemistry.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating specialized fluorinated colorants.

Basic Information

Product Name	2-Amino-5-Fluoropyridine
CAS No.	21717-96-4
Molecular Formula	C5H5FN2
Molecular Weight	112.11 g/mol
Synonyms	5-Fluoro-2-pyridinamine; 5-Fluoro-2-aminopyridine; 2-Pyridinamine, 5-fluoro-; 5-Fluoropyridin-2-amine; 2-Amino-5-fluoropyridine; 5-Fluoro-2-aminopyridine; 2-Amino-5-fluoro-pyridine; 5-Fluoro-2-pyridylamine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.