Description

1,2,3,4-Tetrafluoro-5-Methylbenzene is a fluorinated aromatic compound of significant interest in advanced chemical synthesis. Its value lies in its unique structure, which serves as a versatile building block for introducing fluorine atoms into complex molecules, thereby modifying their physical and chemical properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, leveraging fluorine's ability to increase lipophilicity and environmental persistence of active molecules.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Polymer & Resin Modification: Employed to introduce fluorine into polymer backbones, improving chemical resistance, thermal stability, and surface properties of high-performance materials.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic aromatic substitution, and other transformations to construct complex fluorinated architectures.

Basic Information

Product Name	1,2,3,4-Tetrafluoro-5-Methylbenzene
CAS No.	21622-19-5
Molecular Formula	C7H4F4
Molecular Weight	164.10 g/mol
Synonyms	5-Methyl-1,2,3,4-tetrafluorobenzene; 1,2,3,4-Tetrafluoro-5-methylbenzene; Tetrafluoromethylbenzene; 5-Methyltetrafluorobenzene; 2,3,4,5-Tetrafluorotoluene; α,α,α,α-Tetrafluoro-o-xylene?; Benzene, 1,2,3,4-tetrafluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrafluoro-5-Methylbenzene is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.4 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.