Description

15-Keto Prostaglandin F1Alpha is a specialized oxidized metabolite of prostaglandin F2α, serving as a key analytical reference standard and biochemical research tool. Its primary value lies in its role as a stable marker for the study of prostaglandin metabolism, oxidative stress, and related physiological pathways. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors, particularly those focused on lipidomics, inflammation research, and drug development.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for the quantification and validation of prostaglandin metabolites in biological samples via LC-MS or GC-MS.
• Pharmaceutical Development: Serves as a critical impurity standard and metabolic marker in the development and quality control of prostaglandin-based therapeutics.
• Lipidomics & Metabolomics: A vital component in targeted metabolomics panels for studying eicosanoid pathways, oxidative stress, and inflammatory responses.
• Enzyme Activity Studies: Employed as a substrate or product in assays investigating the activity of prostaglandin dehydrogenases and related enzymes.
• Diagnostic Kit Manufacturing: Utilized in the production of calibration standards for clinical diagnostic kits measuring prostaglandin metabolites.

Basic Information

Item	Details
Product Name	15-Keto Prostaglandin F1Alpha
CAS No.	21562-58-3
Molecular Formula	C₂₀H₃₄O₆
Molecular Weight	370.48 g/mol
Synonyms	15-Keto-PGF1α; 15-Oxo-prostaglandin F1α; 9α,11α,15-Trihydroxy-prost-13-en-1-oic acid; 15-Ketoprostaglandin F1α; 15-Keto-PGF1α; 15-Oxo-PGF1α; PGF1α 15-ketone; 15-Keto-dihydro-PGF2α
EINECS	Contact for details

Quality Control

Our 15-Keto Prostaglandin F1Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the stringent requirements for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and traceability.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic and should be kept under an inert atmosphere when handling to prevent moisture absorption and degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.