Description

1,11Alpha,15S-Trihydroxy-Prost-13E-En-9-One is a high-purity prostaglandin derivative, a key synthetic intermediate in advanced pharmaceutical research and development. This compound matters for its critical role in the synthesis of prostaglandin-based therapeutics, which target a wide range of physiological processes. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing treatments for cardiovascular, ocular, and inflammatory conditions.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of prostaglandin analogs and related bioactive molecules.
• Biochemical Research: Used in studies investigating prostaglandin receptor binding, signal transduction pathways, and cellular metabolism.
• Drug Discovery & Development: Serves as a reference standard and a starting material in medicinal chemistry programs for novel therapeutic agents.
• Ophthalmic Drug Synthesis: A precursor in the manufacturing of prostaglandin-based drugs used to treat glaucoma and ocular hypertension.
• Cardiovascular Research: Employed in preclinical research exploring the role of prostaglandins in vascular tone and platelet aggregation.

Basic Information

Item	Detail
Product Name	1,11Alpha,15S-Trihydroxy-Prost-13E-En-9-One
CAS No.	21562-57-2
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	PGF2α Ethanolamide; 9-Keto-11α,15S-dihydroxy-prost-13-en-1-oic acid ethanolamide; Prostaglandin F2α ethanolamide; 11α,15S-Dihydroxy-9-oxoprost-13-en-1-oic acid 2-hydroxyethylamide; TR 4979; 1,11α,15S-Trihydroxy-9-oxoprost-13-en-1-oic acid ethanolamide; 9-Oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid ethanolamide
EINECS	Contact for details

Quality Control

Our 1,11Alpha,15S-Trihydroxy-Prost-13E-En-9-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and provided upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.