Description

2-Methoxy-4-Nitrobenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl group to create sulfonamides and sulfonate esters. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, antibacterial agents, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the sulfonyl moiety for biological activity.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating sulfonated azo dyes and other colorants with enhanced solubility and fastness properties.
• Polymer Chemistry: Employed to modify polymers and resins, introducing sulfonyl groups to alter material properties like hydrophilicity, adhesion, or thermal stability.
• Peptide and Protein Research: Useful as a protecting group reagent or for modifying amino acid side chains in biochemical studies.
• Chemical Derivatization: Utilized in analytical chemistry to derivative compounds for improved detection via chromatography or spectroscopy.

Basic Information

Product Name	2-Methoxy-4-Nitrobenzenesulfonyl Chloride
CAS No.	21320-91-2
Molecular Formula	C7H6ClNO5S
Molecular Weight	251.64 g/mol
Synonyms	4-Nitro-2-methoxybenzenesulfonyl chloride; 2-Methoxy-4-nitrobenzene-1-sulfonyl chloride; 4-Nitro-o-anisylsulfonyl chloride; NSC 403107; 1-(Chlorosulfonyl)-2-methoxy-4-nitrobenzene; 2-Methoxy-4-nitrobenzenesulphonyl chloride; 4-Nitro-2-methoxybenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Nitrobenzenesulfonyl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under dry conditions. It is incompatible with strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.