Description

5-Nitrotoluene-2-Sulphonyl Chloride is a versatile and reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation agent, introducing the sulfonyl functional group to create compounds with tailored properties. This high-purity intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable and consistent raw materials for research and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the sulfonyl moiety is required for biological activity.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating sulfonated azo dyes and other complex colorants.
• Polymer Modification: Employed to introduce sulfonyl chloride groups into polymer chains for subsequent functionalization or to alter material properties.
• Chemical Research & Development: A valuable reagent in organic chemistry labs for constructing novel molecular architectures and exploring new synthetic pathways.
• Liquid Crystal and Electronic Material Synthesis: Used in the preparation of specialty chemicals for advanced material science applications.

Basic Information

Product Name	5-Nitrotoluene-2-Sulphonyl Chloride
CAS No.	21320-90-1
Molecular Formula	C7H6ClNO4S
Molecular Weight	235.65 g/mol
Synonyms	2-Methyl-5-nitrobenzenesulfonyl chloride; 5-Nitro-o-toluenesulfonyl chloride; 2-Methyl-5-nitrobenzene-1-sulfonyl chloride; 5-Nitro-2-toluenesulfonyl chloride; 5-Nitro-2-methylbenzenesulfonyl chloride; NSC 403107; 5-Nitro-o-tolylsulfonyl chloride
EINECS	244-337-5

Quality Control

Our 5-Nitrotoluene-2-Sulphonyl Chloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting specifications for sensitive synthesis applications. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.