Description

Calcitonin, Human is a polypeptide hormone consisting of 32 amino acids, crucial for calcium and bone metabolism. Its primary value lies in its potent ability to lower blood calcium levels by inhibiting osteoclast activity and promoting renal calcium excretion. This product is essential for research and development in the pharmaceutical and biotechnology sectors, particularly for studies related to osteoporosis, Paget's disease, and hypercalcemia. It serves as a critical reference standard and active pharmaceutical ingredient for therapeutic applications.

Application

• Pharmaceutical research and development for bone metabolism disorders.
• Reference standard in bioanalytical assays and quality control laboratories.
• Active Pharmaceutical Ingredient (API) in the formulation of therapeutic drugs.
• Biochemical studies investigating calcium homeostasis and endocrine pathways.
• Cell culture and in vitro studies to assess osteoclast function.
• Development of diagnostic kits and calibration standards.

Basic Information

Product Name	Calcitonin, Human
CAS No.	21215-62-3
Molecular Formula	C145H240N44O48S2
Molecular Weight	3417.9 g/mol
Synonyms	Human Calcitonin; hCT; Thyrocalcitonin; Calcitonin (human); Salmon Calcitonin (human sequence); Cibacalcin (related); 32-L-Cysteinamide-1,7,32-tricyclo-L-cystine-1,7,32-tricyclo[20.3.0]pentacosa-2,4,6,8,10,12,14,16,18,20,22,24-dodecaene-1,7,32-trisulfane; Calcitonin Gene-Related Peptide I (CGRP-I) (related)
EINECS	244-264-6

Quality Control

Our Calcitonin, Human is produced and tested to meet high-purity standards suitable for research and pharmaceutical development. Each batch undergoes comprehensive analysis including HPLC for purity and peptide mapping, mass spectrometry for identity confirmation, and biological activity testing. A detailed Certificate of Analysis (COA) is provided, documenting compliance with in-house specifications. We support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Biological Activity	≥ 4000 IU/mg
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.