Description

(13E,15S)-15-(Acetyloxy)-9-Oxo-8(12),13-Prostadien-1-Oic Acid Methyl Ester is a high-purity synthetic prostaglandin derivative, a key intermediate in the research and development of advanced pharmaceutical compounds. Its precise stereochemistry and functional groups make it an essential building block for creating novel therapeutic agents targeting inflammation, cardiovascular function, and other critical biological pathways. This compound is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of prostaglandin-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Used as a reference standard and a tool compound in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for the design and development of new chemical entities with potential therapeutic applications.
• Process Development: Employed in the optimization and scale-up of synthetic routes for prostaglandin analogs under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis, chemical biology, and drug discovery.

Basic Information

Item	Details
Product Name	(13E,15S)-15-(Acetyloxy)-9-Oxo-8(12),13-Prostadien-1-Oic Acid Methyl Ester
CAS No.	21174-88-9
Molecular Formula	C23H34O6
Molecular Weight	406.52 g/mol
Synonyms	Methyl (13E,15S)-15-(Acetyloxy)-9-oxoprosta-8(12),13-dien-1-oate; 15(S)-Acetoxy-9-keto-8(12),13-prostadienoic Acid Methyl Ester; Prostaglandin A2 Methyl Ester Acetate; PGA2 Methyl Ester Acetate; 9-Oxo-15(S)-acetoxy-8(12),13-prostadienoic Acid Methyl Ester; 15-Acetoxy-9-oxoprosta-8(12),13-dien-1-oic Acid Methyl Ester; (13E,15S)-15-Acetoxy-9-oxoprosta-8(12),13-dien-1-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (13E,15S)-15-(Acetyloxy)-9-Oxo-8(12),13-Prostadien-1-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep the primary container sealed within a secondary, light-proof container.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.